中國*藥物研究所,是我國歷史最悠久的綜合性創(chuàng)新藥物研究機構(gòu)。對于國際生命科學(xué)發(fā)展的前沿領(lǐng)域以及藥物研究是重要科學(xué)問題,開展創(chuàng)新藥物基礎(chǔ)和應(yīng)用基礎(chǔ)研究,發(fā)展藥物研究新理論、新方法和新技術(shù)。重點圍繞治療惡性腫瘤、心腦血管系統(tǒng)疾病、神經(jīng)精神系統(tǒng)疾病、代謝性疾病、自身免疫性疾病及感染性疾病等開展新藥研發(fā),并加強現(xiàn)代中藥的研發(fā)。
梅雪鋒,美國喬治敦大學(xué)(Georgetown University)化學(xué)博士。中國*研究所研究員,課題組長。此次主要研究領(lǐng)域包括:多晶型,藥物共晶,成藥性評價和藥物開發(fā)中的質(zhì)量控制工作。在口服中藥的晶型研究和采用共結(jié)晶技術(shù)改善難溶性藥物的溶解度,穩(wěn)定性,結(jié)晶度和生物利用度方面的研究。
一、實驗?zāi)康模?/span>
將多晶型藥物進行粉碎,因為目前已經(jīng)是藥粉狀態(tài),需要將藥粉加入試劑一起再研磨,檢測里面的藥物化學(xué)成分,客戶選擇上海凈信Tissuelyser-II進行樣品前處理。
二、實驗地點,實驗材料器材:
中*研究所器材包含Tissuelyser-II高通量組織研磨儀、離心管及適配器、鋼珠等。
三、實驗步驟:
1、準備好離心管及適配器,鋼珠;
2、取藥粉若干,裝入離心管中,裝入鋼珠,加入對應(yīng)容量的試劑;
3、設(shè)置參數(shù)時間后將離心管裝入適配器中固定好,啟動程序,待研磨完成后取出樣品;
4、將研磨好的樣品取出等待下步檢測;
四、實驗結(jié)果:
通過實驗分析滿足客戶的實驗要求,之前用JXFSTPRP-24效果不是很理想,藥粉容易在底部粘黏,跟機器運動方式有很大關(guān)系,建議選用左右式運動方式的研磨儀。
五、注意事項:
1、Tissuelyser-II高通量組織研磨儀操作時一定要擰緊螺帽,左右兩側(cè)一定要配平使用,增加機器使用年限。
2、盡量使用小鋼珠,這樣沖擊力會更小,防止藥粉在底部粘黏。
-
Orbital shaker
-
Standard vacuum freeze dryer
-
Vertical mixer
-
Non-contact ultrasonic DNA interrupter
-
Rotary mixer HS-5
-
Non-contact shaped DNA interrupter
-
Orbital shaker
-
Roller mixer (blood mixer)
-
Dual-channel non-contact energy-concentrated DNA interrupter
-
Rotational viscometer
-
Cup type ultrasonic cell crusher
-
Inching vortex oscillator
-
Handheld ultrasonic cell pulverizer
-
Handheld ultrasonic cell pulverizer
-
Ultra-micro ultrasonic cell crusher
-
Multifunctional vortex oscillator
-
Rotational viscometer
-
Handheld ultrasonic cell crusher
-
Micro centrifuge
-
Integrated ultrasonic cell crusher
-
Handheld ultrasonic cell crusher
-
Multi-tube vortex oscillator
-
Rotational viscometer
-
Micro centrifuge
-
Ultrasonic crusher
-
Integrated ultrasonic cell crusher
-
Nitrogen Blowing Apparatus
-
Ultrasonic cell crusher integrated
-
Ultrasonic crusher
-
Nitrogen Blowing Apparatus
-
Microplate centrifuge
-
Snowflake ice maker
-
Integrated ultrasonic cell crusher
-
Ultrasonic crusher
-
Nitrogen Blowing Apparatus
-
Ultrasonic crusher
-
Split ultrasonic cell disruptor
-
Microplate horizontal centrifuge
-
Snowflake ice maker
-
Ultrasonic cell crusher
-
Integrated ultrasonic cell crusher
-
Nitrogen Blowing Apparatus
-
Round water bath nitrogen blowing instrument
-
Ultrasonic cell crusher
-
Dual-channel non-contact energy-concentrated DNA interrupter
-
Nitrogen Blowing Apparatus
-
Ultrasonic cell crusher
-
Visual nitrogen blowing instrument
-
Intelligent ultrasonic crusher
-
Ultrasonic cell crusher
-
Ultrasonic crusher
-
Constant temperature airtight ultrasonic reactor
-
Non-contact ultrasonic pulverizer
-
Automatic sample fast grinder-24L
-
Soil Ball Mill
-
Microwave ultrasonic extractor
-
Soil Ball Mill
-
Automatic sample fast grinder-32L
-
Planetary Ball Mill
-
Planetary Ball Mill
-
Planetary Ball Mill
-
Automatic sample fast grinder-48L
-
High energy grinder
-
High-throughput soil grinder
-
Glass bead sterilizer
-
Automatic sample fast grinder-64L
-
Automatic sample fast grinder-96L
-
Infrared inoculation loop sterilizer
-
Hair drug detector
-
Infrared inoculation loop sterilizer
-
Hair screening drug detector
-
Hair treatment instrument
-
Portable hair grinder
-
Biological indicator incubator
-
Hair Grinding and Shredder
-
Multi-sample tissue grinding machine-FEIII
-
Multi-sample tissue grinder-FEII
-
Tissue grinder
-
Tissue grinding machine
-
Plant tissue processing system
-
Multi-sample tissue grinding machine-192
-
Multi-sample tissue grinder-96
-
Multi-sample tissue grinder-64
-
Multi-sample tissue grinder -48
-
Multi-sample tissue grinding machine-32
-
Multi-sample tissue grinder-24
-
QuEChERS pre-processing all-in-one machine
-
QuEChERS sample preparation system
-
流體實驗魯爾轉(zhuǎn)接頭
-
細胞定位格子培養(yǎng)皿
-
Thermostatic metal bath
-
μ-Dish 35 mm, high Grid-50 Glass Bottom
-
Thermostatic metal bath
-
Thermostatic metal bath
-
Mini refrigerated metal bath
-
Mini thermostat metal bath
-
六通道載玻片
-
Thermostatic metal bath refrigeration type
-
μ-Dish 35 mm, high tissue culture dish
-
In situ hybridization
-
8孔腔室載玻片
-
Multifunctional cell electric fusion instrument
-
UV crosslinker
-
細胞定位格子培養(yǎng)皿
-
12孔可移除腔室載玻片
-
六通道載玻片0.1
-
魯爾固定連接器-F
-
魯爾固定接頭-M
-
魯爾公接頭
-
魯爾公插頭
-
Molecular hybridization furnace
-
CultureWell?可重復(fù)使用硅膠墊片
-
內(nèi)毒素檢測
-
TH-5熱敏性溫度監(jiān)測儀
-
BAT-12微探針溫度計
-
BAT-10 多功能溫度計
-
灌注管道裝置
-
灌注槽
-
灌注設(shè)備
-
2孔腔室載玻片-無凹液面
-
18孔培養(yǎng)載玻片-扁平版
-
API Coryne
-
常規(guī)培養(yǎng)基
-
CoverWell?成像小室
-
成像墊片(imaging spacer)
-
一體化成像系統(tǒng) (具備AI人工智能技術(shù))
-
High temperature four-module thermostatic metal bath
-
熒光蛋白激發(fā)觀察系統(tǒng)
-
熒光蛋白激發(fā)觀察系統(tǒng)
-
便攜式顯微鏡-帶XY工作臺
-
PM-1 便攜式顯微鏡
-
細胞拉伸系統(tǒng)
-
Culture Well?可移除腔室蓋玻片
-
其他設(shè)備(電生理/IVF)
-
SecureSlip?帶硅膠層蓋玻片
-
活細胞培養(yǎng)系統(tǒng)
-
Three-dimensional mixer
-
磁石培養(yǎng)皿
-
CoverWell?灌流小室
-
CultureWell?多孔腔室蓋玻片
-
共培養(yǎng)載玻片
-
磁座組合式活細胞培養(yǎng)槽
-
3D Centrifugal Cryogenic Grinder
-
Small bead mill/cell bead mill
-
Automatic sample rapid grinder-192
-
Cryogenic Grinder JXFSTPRP-CLN
-
Cryogenic tissue grinder
-
Cryogenic tissue grinder
-
High-speed cryogenic grinding homogenizer
-
Multi-sample tissue grinder-24L
-
High-speed tissue grinding machine KZ-II
-
Multi-channel microbial magnetic bead homogenizer
-
Automatic sample rapid grinding machine
-
Automatic sample rapid grinder-24
-
Immersion liquid nitrogen Cryogenic Grinder
-
Automatic liquid nitrogen freezing grinding machine
-
Automatic sample rapid grinding machine-64
-
Automatic sample rapid grinding machine-48
-
Constant temperature and humidity weighing system
-
Vertical oscillator
-
Multi-sample tissue grinder-192L
-
Multi-sample tissue grinder-96L
-
Multi-sample tissue grinder-64L
-
Cryogenic Grinder (Semi-automatic Liquid Nitrogen Cryogenic Grinder)
-
Multi-sample tissue grinder-32L
-
3D sample tissue grinder
-
Automatic sample rapid grinder-32
-
Automatic sample rapid grinding machine
-
Fully automatic sample rapid cryogenic grinder
-
Fast tissue low-temperature crushing homogenizer
-
Cryogenic Grinding Machine
-
QuEChERS pre-processing all-in-one machine
-
Multi-sample tissue grinder-48L
-
96孔板
-
High energy ball mill
-
3D Cryogenic Grinder
-
3D Centrifugal Cryogenic Grinder
-
Cryogenic tissue grinder
-
Frozen grinder
-
Cryogenic grinder
-
Basic cryogenic grinder
-
Frozen Bone Teeth Crusher
-
Mini grinder
-
Mini Diamond Grinding Machine
-
MINI rapid detection grinder
-
Portable sample grinder
-
Portable sample grinder
-
Automatic sample rapid grinder-96
-
Chlorophyll A grinder
-
Semi-automatic hammer cyclone mill
-
Automatic hammer cyclone mill
-
Low temperature hammer type cyclone mill
-
Multifunctional homogenizer
-
Three-head shock type high-energy ball mill
-
瓊脂糖
-
Water quality chlorophyll grinder
-
Three-dimensional mixer
-
Mortar grinder
-
High-efficiency vibrating disc grinder
-
Fully automatic cryogenic sample processing system
-
Automatic sample rapid grinder
-
Three-dimensional mixer
-
Hot-lid metal bath
-
Three-dimensional high-speed vibration ball mill
-
NTE-2A溫度探針&控制器
-
Automatic homogenizer
-
Beating sample homogenizer
-
Solid phase extraction device
-
Solid Phase Extraction Apparatus
-
組織切片全系統(tǒng)
-
High temperature type CNC super constant temperature bath
-
Vibratron II振動型整流器
-
Automatic rotating sampler
-
Aquatic product animal husbandry solid phase extraction device
-
Knife grinder
-
培養(yǎng)皿載玻片保濕盒
-
玻璃底培養(yǎng)皿
-
串聯(lián)連接管
-
Biological indicator incubator
-
彈性底部培養(yǎng)皿
-
Beating aseptic homogenizer
-
4孔腔室載玻片-無凹液面
-
Oil-free vacuum pump
-
WF-1內(nèi)置沉淀過濾器
-
細胞分離機附屬冷凍系統(tǒng)
-
TCAT-2 動物溫度控制器
-
MTC-1微型溫度控制器
-
定制熱電偶
-
加熱毯WB-1, WB-2
-
TCAT-2配件: 加熱燈HL-1
-
加熱板HP-1M & HP-4M
-
Cross-beating grinder
-
交換器SWT-2
-
Single cell suspension preparation instrument
-
水泵和水箱裝置
-
TS-4MP恒溫顯微鏡載物臺
-
Sample pre-processing machine
-
Fully automatic homogenizer
-
Beating aseptic homogenizer
-
Grinding bead homogenizer
-
Parallel grinder
-
交換器SBT-5
-
細胞趨化載玻片3D
-
Jaw Crusher
-
ibidi Pump System
-
In-line Luer Injection Port
-
μ-Plate Angiogenesis 96 Well
-
μ-Slide y-shaped
-
Constant temperature mixer (refrigeration)
-
Constant temperature mixer
-
μ-Slide I Luer Glass Bottom
-
Culture-Insert 2 Well in μ-Dish 35 mm
-
μ-Slide 8 Well high
-
2D細胞趨化載玻片
-
μ-Slide 15 Well 3D (formerly μ-Slide Angiogenesis)
-
μ-Slide I
-
μ-Dish Microscopy Rack
-
sticky-Slide Chemotaxis
-
Hose Clip
-
Custom-Specific Flow Slides and Channels
-
Dry thermostat
-
減管徑配件
-
微4孔插件
-
Single cell preparation instrument (temperature control)
-
Microplate Shaker
-
Microplate incubator
-
Microplate incubator
-
Oscillator special for microplate
-
硅膠管
-
μ-Slide 18 Well
-
Microplate Heat Sealer
-
器官運輸器
-
單通道載玻片
-
三合一通道載玻片
-
六通道平版載玻片
-
單通道可粘載玻片
-
六通道可粘載玻片
-
Temperature-controlled single cell suspension preparation instrument
-
μ-Slide I Luer 3D
-
Microplate Oscillator
-
梯度混勻器
-
Ricordi? 注射袋
-
High Power Handheld Grinder
-
Bone and Teeth Grinder
-
溫度顯示器
-
溫度探針
-
溫度探針延長線
-
胰島分離機
-
Handheld Grinder
-
分離管道裝置
-
Fully automatic low temperature flip oscillator
-
API 20 E
-
API 20 NE
-
API 20 STAPH
-
API 20 A
-
API NH
-
API Listeria
-
API RapiD 20E
-
Ricordi? 腔室系統(tǒng)
-
Y型連接管
-
無血清培養(yǎng)基
-
細胞培養(yǎng)試劑
-
原代細胞及推薦培養(yǎng)基
-
支原體檢測
-
轉(zhuǎn)染試劑
-
8孔可粘腔室載玻片
-
μ-Dish 35 mm, low
-
New type soil drying box
-
24孔板
-
API ZYM/ API 50CHB/ API 50CHL
-
2孔腔室載玻片
-
4孔腔室載玻片
-
Gradient amplification PCR detection analyzer THG-96G (gradient)
-
Gene amplification instrument PCR instrument THT-96G (gradient type)
-
High-speed grinding homogenizer-192
-
Flip oscillator
-
Fully Automatic Flip Oscillator
-
DIC培養(yǎng)皿蓋/載玻片蓋
-
胰島計數(shù)皿
-
High-throughput sample rapid grinder
-
Medium Flux Grinder
-
High Throughput Grinder
-
High Throughput Tissue Grinder-2018
-
High Throughput Tissue Grinder - GTL64
-
氮化硅彈珠
-
細胞抽樣管
-
菌種保存管
-
胰島細胞計數(shù)儀
-
T型熱電偶金屬線
-
生物流體灌流系統(tǒng)
-
灌流小室
-
灌流管道裝置
-
灌流噴頭
-
灌流腔室過濾器
-
COBE? 2991 血細胞淘洗機
-
閃膠
-
BNC熱電偶
-
通用型探針
-
胰島運輸器
-
API Campy
-
TH-8 熱敏性檢測溫度計
-
BAT7001H溫度計
-
THERMES USB 溫度數(shù)據(jù)采集
-
THERMES USB WFI 溫度數(shù)據(jù)采集
-
針型微探針
-
Ultra High Throughput Tissue Grinder
-
超細IT-系列靈活探針
-
Ultra High Throughput Tissue Grinder
-
臨床探針
-
動物直腸探針
-
RET-2-ISO
-
RET-3-ISO
-
RET-4直腸探針
-
IT系列特氟龍?zhí)结?/p>
-
MT系列針型微探針
-
API 10S
-
靈活可植入探針
- Home
- About us
-
Product
-
Grinder for scientific research
Grinder for scientific research
- Enhanced multi-sample tissue grinder
- Enhanced automatic sample rapid grinder
- Enhanced cryomill
- Multi-sample tissue grinding machine
- Automatic sample rapid grinder
- Cryogenic tissue grinder
- Three-dimensional motion grinder
- Single cell suspension preparation instrument
- Freezer tissue grinder
- Liquid nitrogen Cryogenic Grinder
- High Throughput Tissue Grinder
-
Grinder for analysis?and?detection
Grinder for analysis?and?detection
- Hair drug detector
- Handheld Grinder
- QuEChERS pre-processing all-in-one machine
- Soil/High Energy Planetary Grinder
- Hammer cyclone mill
- Knife grinder
- Multifunctional/Automatic Homogenizer
- Three dimensional vibrating ball mill
- Chlorophyll/soil A grinder
- Mortar grinder
- High-efficiency vibrating disc grinder
- Jaw grinder
- Flap homogenizer
- Bead-milling tissue grinder
- Special grinder for African swine fever
- Three-dimensional mixing instrument
- Miniature bead mill
- Forensic bone and tooth ball mill
- Percussion grinder
- Rotary splitter
-
General?Instruments
General?Instruments
- Ultrasonic cell disruptor
- Ultrasonic equipment
- In situ hybridization instrument/n instrument/crosslinking
- instrument Dry type thermostat/constant temperature mixer
- Vortex mixer/nitrogen purging instrument
- PCR instrument/membrane sealing instrument Snow ice
- Microplate constant temperature shaking incubator
- Orbital shaker/micro centrifuge
- Inoculation loop sterilization/indicator incubator
- Solid phase extraction device/low temperature thermostat
- Snow ice maker/viscometer/lyophilizer
- Flip oscillator
- Soil drying box/humidity box
-
Xiaomei Ultrasound Series
Xiaomei Ultrasound Series
-
Vibrating?sieve?shakers
Vibrating?sieve?shakers
-
Foreign distribution products
Foreign distribution products
-
Grinder for scientific research
- Customers
- News
- Videos
- Case
- Cantact