果蠅是遺傳學研究中常用的模式生物之一，是生物學研究中的重要材料。隨著分子生物學的發展，現代遺傳學研究中很多都需要提取果蠅的DNA以及RNA。果蠅是屬于昆蟲綱雙翅目，形態上也非常接近，那么應該如何提取果蠅的DNA及RNA呢？
從果蠅幼蟲或成蟲頭中分離RNA似乎有點困難，主要是由于角質層的存在。角質層是一種保護性外骨骼，由不溶性膠原蛋白、糖蛋白和脂質等組成。雖然去除角質層可能需要一些力，但可以很容易地做到這一點，而且不會影響RNA的產量或純度。
提取RNA最主要的敵人是RNase(核糖核酸酶)，它可能會悄悄消化掉所有的RNA。RNase是無處不在的，可能在你的手上、頭發上、衣服上，等等。在開始RNase消化掉任何RNA之前，用研磨儀直接將果蠅部分組織進行濕磨，確保RNA不會流失。
上海凈信的工程師為此來到了華中科技大學生命科學院，和專門從事果蠅研究的老師進行了一場關于“提取果蠅（昆蟲）DNA解決方案”的相關性實驗
張珞穎課題組
研究方向：
（1）研究人類突變影響睡眠或晝夜節律的機理；
（2）挖掘和鑒定新的睡眠基因和生物鐘基因，研究其調控睡眠或晝夜節律的機理；
（3）研究睡眠和生物鐘對情緒、學習記憶、新陳代謝等生命過程的影響及調節機理，從而探索睡眠和生物鐘的功能。
主要研究動物：果蠅
實驗操作：2ml離心管，常溫，研磨珠：3mm氧化鋯鋼珠2倍標本體積；按照要求調整好參數
研磨儀安裝調試完畢顯微操作取果蠅頭部
樣品的準備（圖1）放入研磨珠（圖2）
最終研磨效果，均勻細膩
此實驗方法為濕磨方法，經后續DNA、RNA實驗檢測效果非常好。
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Orbital shaker
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Standard vacuum freeze dryer
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Vertical mixer
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Non-contact ultrasonic DNA interrupter
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Rotary mixer HS-5
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Non-contact shaped DNA interrupter
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Orbital shaker
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Roller mixer (blood mixer)
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Inching vortex oscillator
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Handheld ultrasonic cell pulverizer
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Multifunctional vortex oscillator
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Micro centrifuge
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Nitrogen Blowing Apparatus
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Nitrogen Blowing Apparatus
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Planetary Ball Mill
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Planetary Ball Mill
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High energy grinder
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Infrared inoculation loop sterilizer
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Hair drug detector
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Infrared inoculation loop sterilizer
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Biological indicator incubator
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Multi-sample tissue grinding machine-FEIII
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流體實驗魯爾轉接頭
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細胞定位格子培養皿
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Thermostatic metal bath
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μ-Dish 35 mm, high Grid-50 Glass Bottom
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Thermostatic metal bath
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Thermostatic metal bath
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Mini refrigerated metal bath
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Thermostatic metal bath refrigeration type
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μ-Dish 35 mm, high tissue culture dish
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In situ hybridization
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8孔腔室載玻片
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Multifunctional cell electric fusion instrument
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UV crosslinker
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細胞定位格子培養皿
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12孔可移除腔室載玻片
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六通道載玻片0.1
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魯爾固定連接器-F
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魯爾固定接頭-M
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魯爾公接頭
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魯爾公插頭
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Molecular hybridization furnace
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CultureWell?可重復使用硅膠墊片
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內毒素檢測
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TH-5熱敏性溫度監測儀
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BAT-12微探針溫度計
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BAT-10 多功能溫度計
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灌注管道裝置
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灌注槽
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灌注設備
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2孔腔室載玻片-無凹液面
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18孔培養載玻片-扁平版
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API Coryne
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常規培養基
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CoverWell?成像小室
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成像墊片（imaging spacer）
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一體化成像系統 (具備AI人工智能技術)
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High temperature four-module thermostatic metal bath
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熒光蛋白激發觀察系統
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熒光蛋白激發觀察系統
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便攜式顯微鏡-帶XY工作臺
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PM-1 便攜式顯微鏡
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細胞拉伸系統
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Culture Well?可移除腔室蓋玻片
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其他設備(電生理/IVF)
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SecureSlip?帶硅膠層蓋玻片
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活細胞培養系統
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Three-dimensional mixer
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磁石培養皿
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CoverWell?灌流小室
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CultureWell?多孔腔室蓋玻片
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共培養載玻片
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磁座組合式活細胞培養槽
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3D Centrifugal Cryogenic Grinder
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Small bead mill/cell bead mill
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Automatic sample rapid grinder-192
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Cryogenic Grinder JXFSTPRP-CLN
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Cryogenic tissue grinder
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Cryogenic tissue grinder
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High-speed cryogenic grinding homogenizer
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Multi-sample tissue grinder-24L
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High-speed tissue grinding machine KZ-II
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Multi-channel microbial magnetic bead homogenizer
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Automatic sample rapid grinding machine
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Automatic sample rapid grinder-24
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Immersion liquid nitrogen Cryogenic Grinder
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Automatic liquid nitrogen freezing grinding machine
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Automatic sample rapid grinding machine-64
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Automatic sample rapid grinding machine-48
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Constant temperature and humidity weighing system
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Vertical oscillator
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Multi-sample tissue grinder-192L
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Multi-sample tissue grinder-96L
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Multi-sample tissue grinder-64L
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Cryogenic Grinder (Semi-automatic Liquid Nitrogen Cryogenic Grinder)
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Multi-sample tissue grinder-32L
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Automatic sample rapid grinder-32
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Fully automatic sample rapid cryogenic grinder
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Fast tissue low-temperature crushing homogenizer
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QuEChERS pre-processing all-in-one machine
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Multi-sample tissue grinder-48L
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96孔板
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High energy ball mill
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3D Cryogenic Grinder
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3D Centrifugal Cryogenic Grinder
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Cryogenic tissue grinder
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Frozen grinder
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Cryogenic grinder
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Basic cryogenic grinder
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Frozen Bone Teeth Crusher
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Mini grinder
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Mini Diamond Grinding Machine
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MINI rapid detection grinder
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Portable sample grinder
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Automatic sample rapid grinder-96
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Chlorophyll A grinder
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Semi-automatic hammer cyclone mill
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Automatic hammer cyclone mill
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Low temperature hammer type cyclone mill
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Multifunctional homogenizer
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Three-head shock type high-energy ball mill
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瓊脂糖
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Water quality chlorophyll grinder
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Three-dimensional mixer
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High-efficiency vibrating disc grinder
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Solid phase extraction device
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Solid Phase Extraction Apparatus
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組織切片全系統
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High temperature type CNC super constant temperature bath
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Vibratron II振動型整流器
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Automatic rotating sampler
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Knife grinder
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培養皿載玻片保濕盒
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玻璃底培養皿
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串聯連接管
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Biological indicator incubator
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彈性底部培養皿
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Beating aseptic homogenizer
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Oil-free vacuum pump
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定制熱電偶
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Oscillator special for microplate
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硅膠管
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μ-Slide 18 Well
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Microplate Heat Sealer
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器官運輸器
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單通道載玻片
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三合一通道載玻片
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六通道平版載玻片
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六通道可粘載玻片
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Temperature-controlled single cell suspension preparation instrument
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μ-Slide I Luer 3D
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Microplate Oscillator
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梯度混勻器
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Ricordi? 注射袋
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High Power Handheld Grinder
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Bone and Teeth Grinder
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溫度顯示器
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溫度探針延長線
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分離管道裝置
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Fully automatic low temperature flip oscillator
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API 20 E
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API 20 NE
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API 20 STAPH
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API 20 A
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API NH
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API Listeria
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API RapiD 20E
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Ricordi? 腔室系統
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Y型連接管
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無血清培養基
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細胞培養試劑
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原代細胞及推薦培養基
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支原體檢測
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轉染試劑
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8孔可粘腔室載玻片
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μ-Dish 35 mm, low
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New type soil drying box
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24孔板
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API ZYM/ API 50CHB/ API 50CHL
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2孔腔室載玻片
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4孔腔室載玻片
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Gradient amplification PCR detection analyzer THG-96G (gradient)
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Gene amplification instrument PCR instrument THT-96G (gradient type)
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High-speed grinding homogenizer-192
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Flip oscillator
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Fully Automatic Flip Oscillator
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DIC培養皿蓋/載玻片蓋
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胰島計數皿
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High-throughput sample rapid grinder
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Medium Flux Grinder
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High Throughput Grinder
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High Throughput Tissue Grinder-2018
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High Throughput Tissue Grinder - GTL64
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氮化硅彈珠
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細胞抽樣管
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菌種保存管
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胰島細胞計數儀
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T型熱電偶金屬線
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生物流體灌流系統
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灌流小室
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灌流噴頭
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灌流腔室過濾器
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COBE? 2991 血細胞淘洗機
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閃膠
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BNC熱電偶
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通用型探針
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胰島運輸器
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API Campy
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TH-8 熱敏性檢測溫度計
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BAT7001H溫度計
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THERMES USB 溫度數據采集
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針型微探針
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Ultra High Throughput Tissue Grinder
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超細IT-系列靈活探針
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Ultra High Throughput Tissue Grinder
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臨床探針
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動物直腸探針
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RET-2-ISO
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RET-3-ISO
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RET-4直腸探針
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IT系列特氟龍探針
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MT系列針型微探針
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API 10S
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靈活可植入探針
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